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Article

Aequorin variants with improved bioluminescence properties.

Protein engineering, design & selection : PEDS - 1 Apr 2009

Dikici E, Qu X, Rowe L, Millner L, Logue C, Deo S K, Ensor M, Daunert S

Abstract excerpt

The photoprotein aequorin has been widely used as a bioluminescent label in immunoassays, for the determination of calcium concentrations in vivo, and as a reporter in cellular imaging. It is composed of apoaequorin (189 amino acid residues), the imidazopyrazine chromophore coelenterazine and molecular oxygen. The emission characteristics of aequorin can be changed by rational design of the protein to introduce...

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Identifiers

PMID: 19168563
DOI: 10.1093/protein/gzn083
PMCID: PMC2659006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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