Article
Variants at IRX4 as prostate cancer expression quantitative trait loci.
European journal of human genetics : EJHG - 1 Apr 2014
Xu Xing, Hussain Wasay M, Vijai Joseph, Offit Kenneth, Rubin Mark A, Demichelis Francesca, Klein Robert J
Abstract excerpt
Genome-wide association studies (GWAS) have identified numerous prostate cancer-associated risk loci. Some variants at these loci may be regulatory and influence expression of nearby genes. Such loci are known as cis-expression quantitative trait loci (cis-eQTL). As cis-eQTLs are highly tissue-specific, we asked if GWAS-identified prostate cancer risk loci are cis-eQTLs in human prostate tumor tissues. We...
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