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Article

Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set.

Nature communications - 27 Nov 2015

Thibodeau S N, French A J, McDonnell S K, Cheville J, Middha S, Tillmans L, Riska S, Baheti S, Larson M C, Fogarty Z, Zhang Y, Larson N, Nair A, O'Brien D, Wang L, Schaid D J

Abstract excerpt

Multiple studies have identified loci associated with the risk of developing prostate cancer but the associated genes are not well studied. Here we create a normal prostate tissue-specific eQTL data set and apply this data set to previously identified prostate cancer (PrCa)-risk SNPs in an effort to identify candidate target genes. The eQTL data set is constructed by the genotyping and RNA sequencing of 471...

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Share to Databases, Genetic
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

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Share to Quantitative Trait Loci

Share to Regulatory Elements, Transcriptional

Share to Sequence Analysis, RNA

Source

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Identifiers

PMID: 26611117
DOI: 10.1038/ncomms9653
PMCID: PMC4663677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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