Article

Unravelling the Role of Iroquois Homeobox 4 and its Interplay with Androgen Receptor in Prostate Cancer

2023-10-24

Abstract excerpt

<title>Abstract</title> <p>Genome-wide association studies have linked Iroquois-Homeobox 4 (IRX4) as a robust expression quantitative-trait locus associated with prostate cancer (PCa) risk. However, the intricate mechanism and regulatory factors governing IRX4 expression in PCa remain poorly understood. Here, we unveil enrichment of androgen-responsive gene signatures in metastatic prostate tumors exhibiting heig...

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Literature Corpus work: 7034aff1-9f1c-53fa-a83d-5c240a0e9f6d
DOI: 10.21203/rs.3.rs-3295914/v1

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