Article
Molecular dosimetry of DNA adducts in Chinese hamster ovary cells and C3H10T1/2 mouse embryo fibroblast cells treated with benzo[a]pyrene.
Mutagenesis - 1 Jul 1990
Watson W P, Smith R J, Ryan D, Meyer A L
Abstract excerpt
Chromatographic profiles of DNA adducts formed following treatment of Chinese hamster ovary (CHO) cells or C3H10T1/2 mouse embryo fibroblast cells with benzo[a]pyrene (BP), in the presence or absence of rat liver S9 fraction, have been obtained by both direct labelling ([3H]BP) and 32P-post-labelling methods. The principal adduct formed in both cell lines was...
Topics
- Animals
- Benzo(a)pyrene
- Cell Line
- Chromatography, High Pressure Liquid
- Chromatography, Thin Layer
- Cricetinae
- DNA
- DNA Adducts
- DNA Damage
- Mice
- Mutation
- Rats
