Article
ACSM4 polymorphisms are associated with rapid AIDS progression in HIV-infected patients.
Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2014
Guzmán-Fulgencio María, Jiménez José L, Jiménez-Sousa María A, Bellón José M, García-Álvarez Mónica, Soriano Vicente, Gijón-Vidaurreta Paloma, Bernal-Morell Enrique, Viciana Pompeyo, Muñoz-Fernández M Ángeles, Resino Salvador
Abstract excerpt
: Our aim was to explore the association among ACSM4 and PECI polymorphisms and AIDS progression in 454 HIV-infected patients never treated with antiretroviral drugs (146 long-term nonprogressors, 228 moderate progressors, and 80 rapid progressors). For ACSM4 polymorphisms, rs7137120 AA/AG and rs7961991 CC/CT genotypes had higher odds of having a rapid AIDS progression [odds ratio (OR) = 3.21; 95% of confidence...
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