Article
An Observational Study of Genetic Diversity of HIV-1 vpu in Rapid Progressors in India.
Current HIV research - 1 Jan 2023
Gupta Poonam, Rai Arvind, Hans Charoo, Husain Mohammad
Abstract excerpt
BACKGROUND: The genetic diversity in HIV-1 genes affects viral pathogenesis in HIV-1 positive patients. Accessory genes of HIV-1, including vpu, are reported to play a critical role in HIV pathogenesis and disease progression. Vpu has a crucial role in CD4 degradation and virus release. The sequence heterogeneity in the vpu gene may affect disease progression in patients, therefore, the current study was...
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