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Article

Increased prevalence of the alpha-1-antitrypsin (A1AT) deficiency-related S gene in patients infected with human immunodeficiency virus type 1.

Journal of medical virology - 1 Jan 2014

Ferreira Thalita Camêlo da Silva, Sampaio Erika Pereira, Argañaraz Gustavo Adolfo, Gondim Marcos Vinícius Pereira, Shapiro Leland, Argañaraz Enrique Roberto

Abstract excerpt

Large variation exists in susceptibility to infection with Human Immunodeficiency Virus Type 1 (HIV), and disease progression. These observations demonstrate a role for antiretroviral host factors. Several reports describe α1-antitrypsin (A1AT), the most abundant circulating serine protease inhibitor, as a potent suppressor of HIV infection and replication. We identified the normal (M) and most common...

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PMID: 24122823
DOI: 10.1002/jmv.23759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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