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Article

Genetics of hypertension: an assessment of progress in the spontaneously hypertensive rat.

Physiological genomics - 1 Nov 2017

Doris Peter A

Abstract excerpt

The application of gene mapping methods to uncover the genetic basis of hypertension in the inbred spontaneously hypertensive rat (SHR) began over 25 yr ago. This animal provides a useful model of genetic high blood pressure, and some of its features are described. In particular, it appears to be a polygenic model of disease, and polygenes participate in human hypertension genetic risk. The SHR hypertension...

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Identifiers

PMID: 28916635
DOI: 10.1152/physiolgenomics.00065.2017
PMCID: PMC5792135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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