Article
Epistatic interaction between CRHR1 and AVPR1b variants as a predictor of major depressive disorder.
Psychiatric genetics - 1 Dec 2013
Szczepankiewicz Aleksandra, Leszczyńska-Rodziewicz Anna, Pawlak Joanna, Rajewska-Rager Aleksandra, Wilkosc Monika, Zaremba Dorota, Dmitrzak-Weglarz Monika, Skibinska Maria, Hauser Joanna
Abstract excerpt
OBJECTIVE: Genes involved in the regulation of the hypothalamus-pituitary-adrenal axis are responsible for altered susceptibility to mood disorders. The aim of this study was to analyze the possible association of CRHR1 and AVPR1b gene variants with bipolar disorder and major depressive disorder (MDD). METHODS: In the study, we included 486 patients with bipolar disorder and 215 patients with MDD. Consensus...
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