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Article

Association analyses of depression and genes in the hypothalamus-pituitary-adrenal axis.

Acta neuropsychiatrica - 1 Feb 2017

Buttenschøn Henrietta Nørmølle, Krogh Jesper, Nielsen Marit Nyholm, Kaerlev Linda, Nordentoft Merete, Mors Ole

Abstract excerpt

OBJECTIVE: Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been reported in depression. The aim was to investigate the potential association between depression and seven genes regulating or interfering with the HPA axis, including the gene encoding angiotensin converting enzyme (ACE). METHODS: In total, 78 single nucleotide polymorphisms (SNPs) and one insertion/deletion polymorphism were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Hypothalamo-Hypophyseal System

Share to Peptidyl-Dipeptidase A

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 27264499
DOI: 10.1017/neu.2016.26

Genes

ACE
AVP
CRH
CRHR1
CRHR2
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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