Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of corticotropin-releasing hormone receptor1 gene SNP and haplotype with major depression.

Neuroscience letters - 1 Sept 2006

Liu Zhongchun, Zhu Fan, Wang Gaohua, Xiao Zheman, Wang Huiling, Tang Jihua, Wang Xiaoping, Qiu Desheng, Liu Wanhong, Cao Zhijian, Li Wenxin

Abstract excerpt

The dysregulation of the activity of the hypothalamic-pituitary-adrenocortical (HPA) axis system is one of the major neuroendocrine abnormalities in major depression (MD). Many pieces of evidence supported that corticotropin-releasing hormone (CRH) play a role in the pathophysiology of major depression. In this article, whether genetic variations in the corticotropin-releasing hormone receptor1 (CRHR1) gene might...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRF Receptor, Type 1
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CRH gene

Share to CRHR1 gene

Share to Genetic Predisposition to Disease

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Share to Receptors, Corticotropin-Releasing Hormone

Source

Identifiers

PMID: 16815632
DOI: 10.1016/j.neulet.2006.06.016

Genes

CRHR1
CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of corticotropin-releasing hormone receptor1 gene SNP and haplotype with major depression.PMID 16815632Read ↗

Association study of corticotropin-releasing hormone receptor1 gene polymorphisms and antidepressant response in major depressive disorders.Semantic proximity Read ↗

The role of rs242941, rs1876828, rs242939 and rs110402 polymorphisms of CRHR1 gene and the depression: systematic review and meta-analysis.Semantic proximity Read ↗

Effects of corticotropin-releasing hormone receptor 1 SNPs on major depressive disorder are influenced by sex and smoking status.Semantic proximity Read ↗

Association analysis for corticotropin releasing hormone polymorphisms with the risk of major depressive disorder and the response to antidepressants.Semantic proximity Read ↗

Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.Semantic proximity Read ↗

The corticotropin-releasing hormone binding protein is associated with major depression in a population from Northern Sweden.Semantic proximity Read ↗

Interaction between CRHR1 and BDNF genes increases the risk of recurrent major depressive disorder in Chinese population.Semantic proximity Read ↗

Genetic variability at HPA axis in major depression and clinical response to antidepressant treatment.Semantic proximity Read ↗

Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.Semantic proximity Read ↗

Epistatic interaction between CRHR1 and AVPR1b variants as a predictor of major depressive disorder.Semantic proximity Read ↗

Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder.Semantic proximity Read ↗

Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.