Article
Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Keck Martin E, Kern Nikola, Erhardt Angelika, Unschuld Paul G, Ising Marcus, Salyakina Daria, Müller Marianne B, Knorr Carolin C, Lieb Roselind, Hohoff Christa, Krakowitzky Petra, Maier Wolfgang, Bandelow Borwin, Fritze Jürgen, Deckert Jürgen, Holsboer Florian, Müller-Myhsok Bertram, Binder Elisabeth B
Abstract excerpt
Accumulating evidence from animal studies suggests that the corticotropin releasing hormone (CRH) and arginine vasopressin (AVP) neuropeptide systems, contribute to anxiety behavior. To investigate whether polymorphisms in the genes regulating these two systems may alter susceptibility to anxiety disorders in humans, we genotyped 71 single nucleotide polymorphisms (SNPs) in CRH, CRHR1, CRHR2, AVP, AVPR1A, AVPR1B...
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