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Article

Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders.

Archives of general psychiatry - 1 Oct 2007

Dempster Emma L, Burcescu Irina, Wigg Karen, Kiss Eniko, Baji Ildiko, Gadoros Julia, Tamás Zsuzsanna, Kennedy James L, Vetró Agnes, Kovacs Maria, Barr Cathy L

Abstract excerpt

CONTEXT: Disturbances in stress hormones have been implicated in mood disorders, in particular in the hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis. Arginine vasopressin (AVP) plays a crucial role in modulating the HPA axis under stress and does so through a G protein-coupled receptor, vasopressin V1b receptor (AVPR1b). OBJECTIVE: To determine if genetic variation in AVPR1B could be contributing...

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Identifiers

PMID: 17909131
DOI: 10.1001/archpsyc.64.10.1189

Genes

AVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders.PMID 17909131Read ↗

Further genetic evidence implicates the vasopressin system in childhood-onset mood disorders.Semantic proximity Read ↗

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