Article
Genome-wide association studies of maximum number of drinks.
Journal of psychiatric research - 1 Nov 2013
Pan Yue, Luo Xingguang, Liu Xuefeng, Wu Long-Yang, Zhang Qunyuan, Wang Liang, Wang Weize, Zuo Lingjun, Wang Ke-Sheng
Abstract excerpt
Maximum number of drinks (MaxDrinks) defined as "Maximum number of alcoholic drinks consumed in a 24-h period" is an intermediate phenotype that is closely related to alcohol dependence (AD). Family, twin and adoption studies have shown that the heritability of MaxDrinks is approximately 0.5. We conducted the first genome-wide association (GWA) study and meta-analysis of MaxDrinks as a continuous phenotype. 1059...
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