Article
Alcohol consumption indices of genetic risk for alcohol dependence.
Biological psychiatry - 15 Oct 2009
Grant Julia D, Agrawal Arpana, Bucholz Kathleen K, Madden Pamela A F, Pergadia Michele L, Nelson Elliot C, Lynskey Michael T, Todd Richard D, Todorov Alexandre A, Hansell Narelle K, Whitfield John B, Martin Nicholas G, Heath Andrew C
Abstract excerpt
BACKGROUND: Previous research has reported a significant genetic correlation between heaviness of alcohol consumption and alcohol dependence (AD), but this association might be driven by the influence of AD on consumption rather than the reverse. We test the genetic overlap between AD symptoms and a heaviness of consumption measure among individuals who do not have AD. A high genetic correlation between these...
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