Article
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2014
Quillen Ellen E, Chen Xiang-Ding, Almasy Laura, Yang Fang, He Hao, Li Xi, Wang Xu-Yi, Liu Tie-Qiao, Hao Wei, Deng Hong-Wen, Kranzler Henry R, Gelernter Joel
Abstract excerpt
Alcohol dependence (AD) is a moderately heritable phenotype with a small number of known risk genes mapped via linkage or candidate gene studies. We considered 313 males from among 595 members of documented, extended pedigrees in which AD segregates collected in Northern Hunan Province, China. A joint analysis of both males and females could not be performed as the difference in alcohol consumption variance was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.