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Article

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.

Human genetics - 1 Oct 2013

Kapoor Manav, Wang Jen-Chyong, Wetherill Leah, Le Nhung, Bertelsen Sarah, Hinrichs Anthony L, Budde John, Agrawal Arpana, Bucholz Kathleen, Dick Danielle, Harari Oscar, Hesselbrock Victor, Kramer John, Nurnberger John I, Rice John, Saccone Nancy, Schuckit Marc, Tischfield Jay, Porjesz Bernice, Edenberg Howard J, Bierut Laura, Foroud Tatiana, Goate Alison

Abstract excerpt

Maximum number of alcoholic drinks consumed in a 24-h period (maxdrinks) is a heritable (>50 %) trait and is strongly correlated with vulnerability to excessive alcohol consumption and subsequent alcohol dependence (AD). Several genome-wide association studies (GWAS) have studied alcohol dependence, but few have concentrated on excessive alcohol consumption. We performed two GWAS using maxdrinks as an excessive...

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Identifiers

PMID: 23743675
DOI: 10.1007/s00439-013-1318-z
PMCID: PMC3776011

Genes

AUTS2
HIP1
LMO1
PLCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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