Article
A genome screen of maximum number of drinks as an alcoholism phenotype.
American journal of medical genetics - 9 Oct 2000
Saccone N L, Kwon J M, Corbett J, Goate A, Rochberg N, Edenberg H J, Foroud T, Li T K, Begleiter H, Reich T, Rice J P
Abstract excerpt
The Collaborative Study on the Genetics of Alcoholism (COGA) is a multicenter research program to detect and map susceptibility genes for alcohol dependence and related phenotypes. The measure M of "maximum number of drinks consumed in a 24-hour period" is closely related to alcoholism diagnosis in this dataset and provides a quantitative measure to grade nonalcoholic individuals. Twin studies have shown log(M)...
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