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Article

Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry.

Alcoholism, clinical and experimental research - 1 Apr 2009

Karpyak Victor M, Kim Jeong-Hyun, Biernacka Joanna M, Wieben Eric D, Mrazek David A, Black John L, Choi Doo-Sup

Abstract excerpt

BACKGROUND: Mpdz gene variations are known contributors of acute alcohol withdrawal severity and seizures in mice. METHODS: To investigate the relevance of these findings for human alcoholism, we resequenced 46 exons, exon-intron boundaries, and 2 kilobases in the 5' region of the human MPDZ gene in 61 subjects with a history of alcohol withdrawal seizures (AWS), 59 subjects with a history of alcohol withdrawal...

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Identifiers

PMID: 19175764
DOI: 10.1111/j.1530-0277.2008.00888.x
PMCID: PMC2819379

Genes

MPDZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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