Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders.

doi:10.1002/ajmg.b.32231

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Article

Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2014

Kos Mark Z, Glahn David C, Carless Melanie A, Olvera Rene, McKay D Reese, Quillen Ellen E, Gelernter Joel, Chen Xiang-Ding, Deng Hong-Wen, Kent Jack W, Dyer Thomas D, Göring Harald H H, Curran Joanne E, Duggirala Ravi, Blangero John, Almasy Laura

Abstract excerpt

Linkage studies of alcoholism have implicated several chromosome regions, leading to the successful identification of susceptibility genes, including ADH4 and GABRA2 on chromosome 4. Quantitative endophenotypes that are potentially closer to gene action than clinical endpoints offer a means of obtaining more refined linkage signals of genes that predispose alcohol use disorders (AUD). In this study we examine a...

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Identifiers

PMID: 24692236
DOI: 10.1002/ajmg.b.32231
PMCID: PMC4172449

Genes

ADH4
GABRA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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