Article
The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients.
PloS one - 1 Jan 2013
Sun Hongqiang, Wang Fan, Fan Hongzhen, Yan Quanzhi, Cui Kaiyan, Yuan Wei, Zhao Fushuai, Zhao Lili, Yuan Jie, Yang Fude, Kosten Thomas R, Zhang Xiang Yang
Abstract excerpt
OBJECTIVE: Tardive dyskinesia (TD) is a human hyperkinetic movement disorder as a result of potentially irreversible long-term chronic first-generation antipsychotic medications. Unfortunately, mechanisms involved in the development of TD have been poorly understood. Previous studies have indicated that some genetic polymorphisms of immune system and dopamine beta-hydroxylase (DBH) genes may be involved in the...
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