Article
Genetic study of BDNF, DRD3, and their interaction in tardive dyskinesia.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 May 2009
Zai Clement C, Tiwari Arun K, De Luca Vincenzo, Müller Daniel J, Bulgin Natalie, Hwang Rudi, Zai Gwyneth C, King Nicole, Voineskos Aristotle N, Meltzer Herbert Y, Lieberman Jeffrey A, Potkin Steven G, Remington Gary, Kennedy James L
Abstract excerpt
Tardive dyskinesia (TD) is a neuroleptic-induced movement disorder. Its pathophysiology is unclear. The most consistent genetic findings have shown an association with the Ser9Gly polymorphism of the DRD3 gene. However, only few polymorphisms within DRD3 has been tested, and a comprehensive exami...
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