Article
Association between DBH 19bp insertion/deletion polymorphism and cognition in schizophrenia with and without tardive dyskinesia.
Schizophrenia research - 1 Apr 2017
Hui Li, Han Mei, Yin Guang Zhong, Zhang Yingyang, Huang Xu Feng, Qian Zheng Kang, Gu Wei Guo, Gu Xiao Chu, Zhu Xiao Min, Soares Jair C, Ning Yuping, Zheng Yingjun, Du Xiang Dong, Zhang Xiang Yang
Abstract excerpt
Long-term antipsychotic treatment for schizophrenia is associated with the development of tardive dyskinesia (TD), which is involved in increased cognitive impairment. Dopamine beta-hydroxylase (DBH) gene associated with dopamine and norepinephrine systems influences cognition. Schizophrenia with TD have higher DBH activity than those without TD. This study examined whether DBH5'-insertion/deletion (-Ins/Del)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.