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Article

Possible association between DBH 19 bp insertion/deletion polymorphism and clinical symptoms in schizophrenia with tardive dyskinesia.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jun 2015

Hui Li, Han Mei, Huang Xu Feng, Ye Min Jie, Zheng Ke, He Jin Cai, Lv Meng Han, Zhang Bao Hua, Soares Jair C, Zhang Xiang Yang

Abstract excerpt

Overactivity of dopaminergic neurotransmission is a putative mechanism of tardive dyskinesia (TD). Previous studies have found dysfunction in plasma dopamine beta-hydoxylase (DBH) in schizophrenia with TD. Moreover, DBH, whose activity and levels are strongly controlled by the DBH gene, is a key enzyme in the conversion of dopamine (DA) to norepinephrine (NE) associated with excited behavior. This study examined...

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Source

Identifiers

PMID: 25336319
DOI: 10.1007/s00702-014-1327-7

Genes

DBH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Possible association between DBH 19 bp insertion/deletion polymorphism and clinical symptoms in schizophrenia with tardive dyskinesia.PMID 25336319Read ↗

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