Article
Evidence for association of the GLI2 gene with tardive dyskinesia in patients with chronic schizophrenia.
Movement disorders : official journal of the Movement Disorder Society - 15 Dec 2010
Greenbaum Lior, Alkelai Anna, Rigbi Amihai, Kohn Yoav, Lerer Bernard
Abstract excerpt
Tardive dyskinesia (TD) occurs in approximately 20% of patients exposed to long-term antipsychotic treatment and may be influenced by genetic predisposition, in addition to clinical risk factors. In this study, we implemented a two-step approach to identify susceptibility genes for TD. First, we performed a secondary analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) genome-wide...
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