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Article

Association between TNF-α promoter -308A/G polymorphism and tardive dyskinesian Chinese Han patients with schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 27 Apr 2012

Wang Fan, Fan Hongzhen, Sun Hongqiang, Yang Fude, Luo Yixiao, Liu Haibo, Kosten Thomas R, Lu Lin, Zhang Xiang Yang

Abstract excerpt

OBJECTIVE: Previous studies have indicated that the immune may be involved in the pathogenesis of tardive dyskinesia (TD). Some genetic polymorphisms in the human leukocyte antigen (HLA) I and II regions have been associated with TD, and the tumor necrosis factor-α (TNF-α) gene is located in the HLA III region. TNF-α levels in the striatum significantly increased in haloperidol-induced TD in rats. The TNF-α gene...

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PMID: 22227290
DOI: 10.1016/j.pnpbp.2011.12.007

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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