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Article

CHRM2 and GRIN2A polymorphisms in tardive dyskinesia and cognitive impairments in Chinese Han schizophrenia.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2026

Lu Chenghao, Wang Linxuan, Wang Jing, Zeng Min, Zhang Xiao, Li Yanzhe, Zhang Xiaofei, Liu Nannan, Chi Jinghui, Wang Lili, Li Shen

Abstract excerpt

The genetic mechanisms underlying tardive dyskinesia (TD) are crucial for understanding its development. This study aimed to examine the association between single nucleotide polymorphisms (SNPs) in the Glutamate Ionotropic Receptor NMDA Type Subunit (GRIN2A) and Cholinergic Receptor Muscarinic 2 (CHRM2) genes and their interactions with the susceptibility, severity of symptoms, and cognitive function of TD in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40445323
DOI: 10.1007/s00702-025-02954-8

Genes

CHRM2
GRIN2A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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