Article
A novel statistic for genome-wide interaction analysis.
PLoS genetics - 23 Sept 2010
Wu Xuesen, Dong Hua, Luo Li, Zhu Yun, Peng Gang, Reveille John D, Xiong Momiao
Abstract excerpt
Although great progress in genome-wide association studies (GWAS) has been made, the significant SNP associations identified by GWAS account for only a few percent of the genetic variance, leading many to question where and how we can find the missing heritability. There is increasing interest in genome-wide interaction analysis as a possible source of finding heritability unexplained by current GWAS. However,...
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