Article
Genome-wide gene and pathway analysis.
European journal of human genetics : EJHG - 1 Sept 2010
Luo Li, Peng Gang, Zhu Yun, Dong Hua, Amos Christopher I, Xiong Momiao
Abstract excerpt
Current GWAS have primarily focused on testing association of single SNPs. To only test for association of single SNPs has limited utility and is insufficient to dissect the complex genetic structure of many common diseases. To meet conceptual and technical challenges raised by GWAS, we suggest gene and pathway-based GWAS as complementary to the current single SNP-based GWAS. This publication develops three...
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