Article
The macromelanophore locus and the melanoma oncogene Xmrk are separate genetic entities in the genome of Xiphophorus.
Genetics - 1 Aug 1998
Weis S, Schartl M
Abstract excerpt
Fish of the genus Xiphophorus are polymorphic for black pigmentation patterns. Certain intra- or interspecific hybrids exhibit enhanced expression of these patterns, leading in many cases to malignant melanoma. Because no recombination was ever observed between the pattern information and the gen...
Topics
- Animals
- Base Sequence
- Crosses, Genetic
- Cyprinodontiformes
- DNA
- DNA Primers
- Female
- Fish Diseases
- Fish Proteins
- Genome
- Hybridization, Genetic
- Male
- Melanoma
- Melanophores
- Molecular Sequence Data
- Oncogenes
- Phenotype
- Phylogeny