Article
Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0.
BMC genomics - 26 Jul 2013
Teumer Alexander, Ernst Florian D, Wiechert Anja, Uhr Katharina, Nauck Matthias, Petersmann Astrid, Völzke Henry, Völker Uwe, Homuth Georg
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) using array-based genotyping technology are widely used to identify genetic loci associated with complex diseases or other phenotypes. The costs of GWAS projects based on individual genotyping are still comparatively high and increase with the size of study populations. Genotyping using pooled DNA samples, as also being referred as to allelotyping approach,...
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