Article
Most pooling variation in array-based DNA pooling is attributable to array error rather than pool construction error.
European journal of human genetics : EJHG - 1 Apr 2007
Macgregor Stuart
Abstract excerpt
Genome-wide association (GWA) approaches are important in complex disease gene mapping studies but are often prohibitively expensive. Array-based DNA pooling has been shown to offer substantial cost savings compared with individual genotyping. This reduced cost potentially brings well-powered GWA studies well within the reach of most laboratories. The main factor, which affects the efficiency of pooling compared...
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