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Article

Dynamics of the full length and mutated heat shock factor 1 in human cells.

PloS one - 1 Jan 2013

Herbomel Gaëtan, Kloster-Landsberg Meike, Folco Eric G, Col Edwige, Usson Yves, Vourc'h Claire, Delon Antoine, Souchier Catherine

Abstract excerpt

Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress. Upon stress, HSF1 binds to and transcribes hsp genes and repeated satellite III (sat III) sequences present at the 9q12 locus. HSF1 binding to pericentric sat III sequences forms structures known as nuclear stress bodies (nSBs). nSBs represent a natural...

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Source

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Identifiers

PMID: 23861773
DOI: 10.1371/journal.pone.0067566
PMCID: PMC3704536

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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