Article

Inducible transcriptional condensates drive 3D genome reorganization in the heat shock response

2021-10-28

Abstract excerpt

<h4>SUMMARY</h4> Mammalian developmental and disease-associated genes concentrate large quantities of the transcriptional machinery by forming membrane-less compartments known as transcriptional condensates. However, it is unknown whether these structures are evolutionarily conserved, capable of stress-inducible gene activation or involved in 3D genome reorganization. Here, we identify inducible transcriptional c...

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Literature Corpus work: f55b712a-1f84-58ec-bce5-c93c1a717b32
DOI: 10.1101/2021.10.27.466170

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