Article

Cell cycle arrest explained the observed bulk 3D genomic alterations in response to long term heat shock for mammalian cells

2021-12-07

Abstract excerpt

Heat shock is a common environmental stress, while the response of the nucleus to it remains controversial in mammalian cells. Acute reaction and chronic adaptation to environmental stress may have distinct internal rewiring in the gene regulation networks. However, this difference remains largely unexplored. Here, we report that chromatin conformation and chromatin accessibility respond differently in short- and...

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Literature Corpus work: 8a0cfeab-e203-5420-9b93-bbb119e40eb3
DOI: 10.1101/2021.12.07.471582

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