Article
Differential recognition of heat shock elements by members of the heat shock transcription factor family.
The FEBS journal - 1 Apr 2009
Yamamoto Noritaka, Takemori Yukiko, Sakurai Mayumi, Sugiyama Kazuhisa, Sakurai Hiroshi
Abstract excerpt
Heat shock transcription factor (HSF), an evolutionarily conserved stress response regulator, forms trimers and binds to heat shock element (HSE), comprising at least three continuous inverted repeats of the sequence 5'-nGAAn-3'. The single HSF of yeast is also able to bind discontinuously arranged nGAAn units. We investigated interactions between three human HSFs and various HSE types in vitro, in yeast cells,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
