Article
Mannose binding lectin and mannose binding lectin-associated serine protease-2 genes polymorphisms in human T-lymphotropic virus infection.
Journal of medical virology - 1 Oct 2013
Coelho Antonio Victor Campos, Brandão Lucas André Cavalcanti, Guimarães Rafael Lima, Loureiro Paula, de Lima Filho José Luiz, de Alencar Luiz Cláudio Arraes, Crovella Sergio, Segat Ludovica
Abstract excerpt
Variations in genes involved in the immune response pathways may influence the interaction between viruses (such as Human T-lymphotropic virus, HTLV-1) and the host. The mannose binding lectin (MBL) and its associated serine protease type 2 (MASP-2) promote the activation of the lectin pathway of the complement system. As the interaction of complement system with HTLV-1 is not well understood, the MBL2...
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