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Article

Influence of mannose-binding lectin on HIV infection and tuberculosis in a Western-European population.

Molecular immunology - 1 Jul 2006

Garcia-Laorden M Isabel, Pena M Jose, Caminero Jose A, Garcia-Saavedra Ayoze, Campos-Herrero M Isolina, Caballero Araceli, Rodriguez-Gallego Carlos

Abstract excerpt

Mannose-binding lectin (MBL) is a serum lectin that mediates phagocytosis and activates complement. Its deficiency has been associated with increased susceptibility to infectious diseases, mainly in childhood. However, non-producer mbl-2 alleles are common in most populations, suggesting a selective advantage of these alleles. We have analysed the association of mbl-2 structural and promoter polymorphisms with...

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Identifiers

PMID: 16500704
DOI: 10.1016/j.molimm.2006.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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