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MBL2 gene polymorphisms related to HIV-1 infection susceptibility and treatment response.

Human immunology - 1 Feb 2023

Bouqdayr Meryem, Baba Hanâ, Saih Asmae, Abbad Anass, Hamdi Salsabil, Marih Latifa, Sodqi Mustapha, Ouladlahsen Ahd, Marhoum El Filali Kamal, Moussamih Samya, Saile Rachid, Kettani Anass, Wakrim Lahcen

Abstract excerpt

Human Mannose-binding lectin (MBL) is a protein encoded by MBL2 gene involved in the activation of the lectin-complement pathway. Several studies emphasized the role of MBL2 gene in several infectious diseases' susceptibility, including HIV-1 infection. We aim to investigate the impact of 10 MBL2 gene polymorphisms located in the promoter, 5'UTR and exon 1 regions on HIV-1 physiopathology. The polymorphisms...

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Identifiers

PMID: 36257838
DOI: 10.1016/j.humimm.2022.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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