Article
Association between mannose-binding lectin and HIV infection and progression in a Chinese population.
Molecular immunology - 1 Dec 2009
Tan Yajun, Liu Lifeng, Luo Peng, Wang Anxu, Jia Tianjun, Shen Xinliang, Wang Man, Zhang Shumin
Abstract excerpt
Mannose-binding lectin (MBL) is a circulating pattern recognition molecule involved in the innate immune system that mediates phagocytosis and activates complement by binding to a carbohydrate extremity. Some MBL genetic polymorphisms result in deficient protein levels and increased susceptibility to infection. The objective of this study was to investigate the association between MBL2 exon 1 polymorphisms, serum...
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