Article
Genetic association analysis of ITGB3 polymorphisms with age at onset of schizophrenia.
Journal of molecular neuroscience : MN - 1 Oct 2013
Wang Ke-Sheng, Liu Xuefeng, Arana Tania Bedard, Thompson Nicholas, Weisman Henry, Devargas Cecilia, Mao Chunxiang, Su Brenda Bin, Camarillo Cynthia, Escamilla Michael A, Xu Chun
Abstract excerpt
Schizophrenia (SCZ) is a debilitating disorder with a prevalence of approximately 1 % worldwide. SCZ is known to have a high degree of genetic and clinical heterogeneity and is a major health problem worldwide. The integrin-β 3 subunit gene (ITGB3) gene at 17q21.32 has been implicated in psychiatric disorders. We therefore hypothesized that ITGB3 gene polymorphisms might also play a role in SCZ and age at onset...
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