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Article

Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia.

Neuropsychobiology - 1 Jan 2016

Chow Tze Jen, Tee Shiau Foon, Yong Hoi Sen, Tang Pek Yee

Abstract excerpt

BACKGROUND: Age at onset (AAO) is a known prognostic indicator for schizophrenia and is hypothesized to correlate with cognition and symptom severity. TCF4 and AKT1 are schizophrenia risk genes involved in cognitive functions. The current study examined the interactive effects of TCF4 and AKT1 variants with gender, family history of psychiatric disorders and ethnicity on the AAO of schizophrenia. METHODS: This...

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Source

Identifiers

PMID: 27305091
DOI: 10.1159/000446285

Genes

TCF4
AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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