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Article

Genome-wide association analysis of age at onset in schizophrenia in a European-American sample.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2011

Wang Ke-Sheng, Liu Xuefeng, Zhang Qunyuan, Aragam Nagesh, Pan Yue

Abstract excerpt

We performed a genome-wide association analysis to identify genetic variants influencing age at onset (AAO) and examine gene × gender interactions for AAO in schizophrenia (SCZ) using a European-American sample (1,162 cases). Linear regression model in PLINK was used to test for associations with AAO while the GxE option was chosen to test for the influence of gene × gender interactions. The most significant...

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PMID: 21688384
DOI: 10.1002/ajmg.b.31209

Genes

RYR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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