Article
Tumour diploidy and survival in breast cancer patients with BRCA2 mutations.
Breast cancer research and treatment - 1 Jul 2013
Tryggvadottir Laufey, Olafsdottir Elinborg J, Olafsdottir Gudridur H, Sigurdsson Helgi, Johannsson Oskar T, Bjorgvinsson Einar, Alexiusdottir Kristin, Stefansson Olafur A, Agnarsson Bjarni A, Narod Steven A, Eyfjord Jorunn E, Jonasson Jon G
Abstract excerpt
It is not well known to what extent carrying a BRCA2 mutation affects the survival of women with breast cancer and prognostic factors among BRCA2-positive women warrant investigation. Using a record linkage approach we compared the long-term survival in carriers and noncarriers of an inherited BRCA2 founder mutation (999del5), and sought to identify prognostic factors among the BRCA2 mutation-positive subset,...
Topics
- Adult
- Aged
- BRCA2 Protein
- Breast Neoplasms
- Diploidy
- Female
- Humans
- Middle Aged
- Mutation
- Prognosis
- Survival Analysis