Article
A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes.
Nature genetics - 1 May 1996
Thorlacius S, Olafsdottir G, Tryggvadottir L, Neuhausen S, Jonasson J G, Tavtigian S V, Tulinius H, Ogmundsdottir H M, Eyfjörd J E
Abstract excerpt
The BRCA2 gene on chromosome 13 has been shown to be associated with familial male and female breast cancer. Here we describe a study on BRCA2 in 21 Icelandic families, including 9 with male breast cancer. We have previously reported linkage to the BRCA2 region in an Icelandic male breast cancer family and subsequently found a strong indication of linkage to BRCA2 and the same BRCA2 haplotype in breast cancer...
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