Article
Oestrogen receptor status, treatment and breast cancer prognosis in Icelandic BRCA2 mutation carriers.
British journal of cancer - 27 Sept 2016
Jonasson Jon G, Stefansson Olafur A, Johannsson Oskar T, Sigurdsson Helgi, Agnarsson Bjarni A, Olafsdottir Gudridur H, Alexiusdottir Kristin K, Stefansdottir Hrefna, Munoz Mitev Rodrigo, Olafsdottir Katrin, Olafsdottir Kristrun, Arason Adalgeir, Stefansdottir Vigdis, Olafsdottir Elinborg J, Barkardottir Rosa B, Eyfjord Jorunn E, Narod Steven A, Tryggvadóttir Laufey
Abstract excerpt
BACKGROUND: The impact of an inherited BRCA2 mutation on the prognosis of women with breast cancer has not been well documented. We studied the effects of oestrogen receptor (ER) status, other prognostic factors and treatments on survival in a large cohort of BRCA2 mutation carriers. METHODS: We identified 285 breast cancer patients with a 999del5 BRCA2 mutation and matched them with 570 non-carrier patients....
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