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Article

BRCA2, but not BRCA1, mutations account for familial ovarian cancer in Iceland: a population-based study.

European journal of cancer (Oxford, England : 1990) - 1 Dec 2004

Rafnar Thorunn, Benediktsdottir Kristrun R, Eldon Bjarki J, Gestsson Thorgeir, Saemundsson Hafsteinn, Olafsson Karl, Salvarsdottir Anna, Steingrimsson Eirikur, Thorlacius Steinunn

Abstract excerpt

A single founder mutation in each of the BRCA genes has been identified in Iceland. The frequency of the BRCA1 G5193A and BRCA2 999del5 mutations in all ovarian cancer patients diagnosed over the period 1991-2000 was determined. Mutation status was correlated with family history, tumour morphology and age at diagnosis. Samples from 86% of cases (179 carcinomas and 74 borderline tumours) were available. In the...

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Identifiers

PMID: 15571962
DOI: 10.1016/j.ejca.2004.09.008

Genes

BRCA2
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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