BRCA2mutation carriers, reproductive factors and breast cancer risk

Abstract excerpt

BACKGROUND: Germline mutations in the BRCA genes dramatically increase the risk of breast cancer. In the general population, breast cancer risk is affected by age at menarche, by age at first birth, by the number of births and by the duration of breast feeding. Whether this is true for mutation carriers is not clear. METHODS: In a case-control study, nested in a population-based cohort of the Icelandic Cancer...

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