Article
Hereditary breast/ovarian cancer: clinicopathological characteristics and survival of BRCA2 positive and negative cases.
Journal of experimental therapeutics & oncology - 1 Jan 2008
Syamala Vani, Syamala Volga S, Sreeja Leelakumari, Raveendran Praveenkumar B, Vijayalekshmi R V, Sheeja V R, Santhi S, Kuttan Ratheesan, Abraham Elizabeth K, Ankathil Ravindran
Abstract excerpt
The clinical and pathological characteristics and prognostic outcome of patients with hereditary breast/ovarian cancer and BRCA2 mutations are poorly known. Hence, the present study aimed to correlate the BRCA2 mutation status with clinical characteristics and overall survival of 102 breast/ovarian cancer patients in Kerala, South India. All the coding regions of BRCA2 genes were PCR amplified and analyzed for...
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